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Frontline Plus For Dogs and Puppies Free Shipping Kills 100% of Fleas and Ticks within 24 to 48 hours. Contains Fipronil, a special ingredient that spreads by way of your pet's body oils to nullify a parasite's nervous system, causing paralysis and death. Frontline Plus® also contains methoprene, an Insect Growth Regulator, which makes it impossible for an insect to grow or reproduce. Kills Fleas before they have the chance to lay eggs - thus breaking the Flea life cycle. Generally kills Fleas before they bite, thus reducing the risk of sickness, allergies and disease transmission. Water Resistant - Continues to kill Fleas after swimming, shampooing, rain or exposure to sunlight. In pre-measured, child proof, easy-to-use applicator tubes. Stain and Odor Free! Extra Information Frontline Plus® is a monthly application that kills 100% of fleas and their larvae within 24 to 48 hours. In addition, Frontline Plus® breaks the parasite life cycle, thus preventing them from laying eggs and reproducing. Frontline Plus® is applied to the back of the neck on cats and between the shoulder blades on dogs. It spreads naturally on the skin surface at the hair root level, aided by body movement to provide whole body coverage. Frontline Plus® a is water-resistant flea medication, so it continues to kill fleas even after a shampooing, swimming, rain or exposure to sunlight. Frontline Plus® is for Dogs and Cats over 8 weeks old. Do not use Frontline Plus® on Dogs less than 11 lbs